Professor Sean M. Richards is as a UC Foundation Professor in the Department of Biology, Geology and Environmental Science, a member of the UTC Council of Scholars and holds a joint appointment in the Department of Obstetrics and Gynecology at the University of Tennessee Health Science Center College of Medicine. Since 2002 his lab has investigated the potential for toxicant exposure to people living in Chattanooga. This was initially facilitated by the first NIEHS grant awarded to UTC. That grant was used to investigate the potential for PAH and metal exposure and effects to Chattanoogans from Chattanooga Creek. Dr. Richards’ laboratory (in conjunction with Southern Illinois University) determined the types of compounds present and the potential for effects in humans. This work was facilitated by high pressure liquid chromatography (PAH quantitation) and atomic absorption spectroscopy (metal quantitation) and by measuring biomarkers of exposure in small mammals inhabiting the floodplains of Chattanooga Creek. These data were then used to estimate likelihood of exposure and effects through probabilistic risk assessments. Hamilton County, TN has a relative high incidence of low birth weight (full-term infants with a birth weight below 2500 g).